Canzar Lab
High-throughput next-generation sequencing (NGS) technology has become a ubiquitous tool in the study of a wide range of biological and biomedical questions. NGS instruments produce a huge number of short DNA sequences, or 'reads', each of which carries little information by itself. These reads therefore have to be pieced together by well-engineered algorithms to reconstruct biologically meaningful measurments. The lab's goal is the development of accurate mathematical models, efficient algorithms, and usable software to solve these complex, high-dimensional puzzles.